内容摘要：Stone sculpture, once a thriving local industry, has suffered due to

Stone sculpture, once a thriving local industry, has suffered due to

While Montgomery is thrilled with Looney’s progress, he’s done most work using Revivicor pigs with just, in a xenotransplant last April and in research with the deceased.

“Our feeling is, you know, less is more,” said Montgomery, noting it’s easier to mass produce pigs with fewer gene alterations. Looney’s transplant offers a chance to compare “really how much difference those additional gene edits are making.”In Boston, eGenesis has still another approach – a whopping 69 gene edits. In addition to 10 genetic alterations to improve human compatibility, genes linked to certain pig viruses also are inactivated.Researchers feel pressure to show if pig organs can keep people alive much longer than a few months, said eGenesis’ Curtis. If not, the question will be “do we have the right gene edits?”

The balance is choosing participants sick enough to qualify but not so sick they have no chance.“There’s a tremendous number of patients who would be very willing, very willing to do this,” said Dr. Silke Niederhaus of the University of Maryland, who isn’t involved in xenotransplant research but watches it closely.

Niederhaus became a kidney transplant surgeon because around her 12th birthday, one saved her life. That kidney lasted three decades. When it failed, it took five years to find another. So she understands the draw of pig research, and urges people to learn their odds of getting a human kidney before volunteering.

If they’re younger, healthier or have a living donor, “I would probably say go with what’s known and what’s proven,” Niederhaus said. But if they’re older and dialysis is starting to fail, “maybe it’s worth taking the risk.”Yet unlike his predecessors, Francis incrementally conveyed through his actions, formal statements and occasional casual remarks that he wanted the church

Among activists, there was frustration over the lack of a doctrinal breakthrough, but still there was gratitude this week for his unabashed warmth toward them.A public blessing ceremony with hundreds of believers takes place in front of the Cologne Cathedral in Cologne, Germany, Sept. 20, 2023. (AP Photo/Martin Meissner, File)

A public blessing ceremony with hundreds of believers takes place in front of the Cologne Cathedral in Cologne, Germany, Sept. 20, 2023. (AP Photo/Martin Meissner, File)Francis, who died Monday, “was a transformational leader who included LGBTQ people in historic ways,” said Sarah Kate Ellis, CEO of the U.S.-based advocacy group GLAAD, who met twice with the pope. “His principles of empathetic listening, inclusion, and compassion are exactly what this divided world needs right now.”